Search results for "Ageing genes."

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Analysis of Candidate Genes in Celiac Disease: A Tool to Identify Life-Threatening Associated Genes?

2006

The authors have recently reported that celiac patients show a proinflammatory cytokine genetic profile characterized by the contemporaneous presence of both the tumour necrosis factor-alpha-308A and the interferon-gamma +874T allele-positive genotypes. The same alleles are considered risk factors for aging associated disease, whereas an anti-inflammatory cytokine genotype profile might be associated with an extended life expectancy. This paper reports data on the 1249-1250InsACAA/Non-Ins transforming growth factor (TGF)-beta2, a multifunctional anti-inflammatory cytokine, polymorphism distribution in 88 celiac disease (CD) patients, 99 age- and sex-matched controls, and 2895-year-old healt…

AdultMaleAgeing genes.AgingCandidate geneGenotypemedicine.medical_treatmentLongevityDiseaseBiologyProinflammatory cytokineInterferon-gammaTransforming Growth Factor beta2Gene FrequencyTransforming Growth Factor betaPolymorphism (computer science)GenotypemedicineHumansAlleleAgedAged 80 and overPolymorphism GeneticTumor Necrosis Factor-alphaMiddle AgedGenotype frequencyCeliac DiseaseCytokineImmunologyFemaleGeriatrics and GerontologyRejuvenation Research

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